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White willow bark: what it may help and who should never take it

By the Life in Good Form editors. Updated 2026-10-15.

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Quick answerWhite willow bark contains salicin, the compound aspirin was developed from, and is sold for pain, fever and joint aches. Memorial Sloan Kettering Cancer Center (MSK) says a few studies suggest it may help low back pain, results are mixed for osteoarthritis, and studies were negative for rheumatoid arthritis. It can cause aspirin-like side effects. Do not take it if you are allergic to aspirin, take blood thinners or NSAIDs, have ulcers, asthma or bleeding problems, are pregnant or nursing, or are planning surgery. Never give it to children, because of the risk of Reye syndrome.
Our picks at a glance
  • Willow bark extract, 15% salicin. Best for: Adults with occasional back pain whose doctor has okayed it. See options on Amazon
  • Organic cut white willow bark. Best for: Adults who prefer an herbal tea. See options on Amazon
  • White willow bark capsules, plain bark. Best for: Adults comparing single-herb capsules. See options on Amazon

Compare the picks and what to watch out for

What white willow bark is

Willow is a tree native to Europe, Asia and parts of North America. MSK says its bark has been used for thousands of years in China and Europe for fever and pain. Its main active compound is salicin, and aspirin was developed from salicin.

MSK adds that salicin is not the only active part: catechols and flavonoids in the bark also contribute to its anti-inflammatory effects in lab studies. Supplements are often standardized to salicin; NOW Foods' Willow Bark Extract lists Salix species bark with at least 15% salicin.

What the research shows

UseWhat MSK reports
Low back painA few trials suggest it may help
OsteoarthritisMixed results
Rheumatoid arthritisNegative findings
FeverThought to act like aspirin; no clinical trials
Weight lossNo studies

Back pain. MSK notes clinical trials suggest willow bark extract can help low back pain, including a randomized double-blind study of flare-ups. This is the use with the most support.

Arthritis. Osteoarthritis results are mixed, and studies in rheumatoid arthritis were negative.

Not an aspirin substitute. Aspirin has been studied for heart disease and cancer prevention, but MSK says willow bark should not be used in place of aspirin because its potency varies. A direct comparison between the benefits of aspirin and willow bark cannot be made.

Who should not take willow bark

MSK lists these situations in which you should not take willow bark:

MSK also says to stop willow bark before surgery or chemotherapy because of bleeding risk. NOW Foods' label says not for pregnant or nursing women and to consult a physician if you have a bleeding disorder or ulcers or plan surgery.

Never give willow bark to children

MSK warns that children should not be given willow bark because of the potential for Reye syndrome, a serious condition linked to aspirin use in children. MSK also describes a fatal case of liver failure in a 28-month-old boy treated for a respiratory infection with acetaminophen and a tea containing willow bark.

Side effects and case reports

Reading a willow bark label

What to look for when you buy

Willow bark extract, 15% salicin

Best for: Adults with occasional back pain whose doctor has okayed it

NOW Foods lists 800 mg of extract with at least 15% salicin per 2 capsules, taken with food as needed.

Watch out: Not with aspirin allergy, blood thinners, NSAIDs, ulcers, asthma, pregnancy or before surgery. Never for children.

See options on Amazon

Organic cut white willow bark

Best for: Adults who prefer an herbal tea

Cut and sifted bark is sold for making tea.

Watch out: Salicin content varies. Same cautions as capsules, and never give it to children.

See options on Amazon

White willow bark capsules, plain bark

Best for: Adults comparing single-herb capsules

Single-herb capsules avoid blends that add other bleeding-related ingredients.

Watch out: Check whether salicin is stated. Follow the label and stop before surgery.

See options on Amazon
When to talk to a doctor: Do not take willow bark if you are allergic to aspirin, take blood thinners or NSAIDs, have ulcers, asthma or a bleeding disorder, are pregnant or nursing, or are planning surgery or chemotherapy. Never give willow bark to children. Talk with your doctor about ongoing pain.

Questions people ask

Is white willow bark the same as aspirin?
No. Aspirin was developed from salicin in willow bark, but potency varies, and MSK says willow bark should not replace aspirin.
What is white willow bark good for?
A few trials suggest it may help low back pain. Results are mixed for osteoarthritis and negative for rheumatoid arthritis.
Can I take willow bark with ibuprofen?
MSK says not to. Taking it with NSAIDs may raise the risk of stomach and intestinal damage and bleeding.
Can children take white willow bark?
No. Children should not be given willow bark because of the risk of Reye syndrome.
How much white willow bark should I take?
Follow the label. NOW Foods directs 2 capsules 1 to 2 times daily as needed with food.

Sources

Sources checked 2026-10-15.