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Vaginal moisturizer

By the Life in Good Form editors. Updated 2026-10-15.

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Moisturizer vs lubricant

You can use both, following each product's label. For lubricant types, see our personal lubricant guide.

Why vaginal dryness happens

The NIA says some women have vaginal dryness during the menopausal transition, and may also experience a tightening of the vaginal opening, burning, itching and dryness, called vaginal atrophy. Replens says vaginal dryness is most often associated with the normal decline or fluctuation of estrogen.

Dryness can make sex uncomfortable, which is one reason the NIA lists both over-the-counter products and prescription treatments.

How an internal moisturizer works

Replens describes its Long-Lasting Vaginal Moisturizer as using bio-adhesive technology that attaches to dry cells and delivers continuous moisture, and says it is estrogen-free. It comes two ways:

• Single-use applicators: 8 applications, each lasting 3 days, for an up to 24-day supply.
• Tube with reusable applicator: a 35g tube with 14 applications, each lasting 3 days, for an up to 42-day supply.

Replens recommends using it at least 2 hours before intercourse to allow proper moisturization.

How to use an applicator

Replens gives these steps for its pre-filled applicator:

• Wash your hands, and remove the applicator from its sealed wrapper.
• Flick the thin tip down several times so the contents move into the tip, then twist off the tab. Do not use scissors or sharp tools to open it.
• Sitting or lying on your back with knees bent, gently insert the open end well into the vagina.
• Squeeze the thick end firmly 2-3 times to deposit the gel.
• Remove the applicator and discard it.

Follow the instructions for the reusable applicator if you buy the tube, including washing it between uses.

Products for the outside: vulvar moisturizers

Some products are made only for the vulva, the outer skin. DIVA says its Moisturizer contains Ceramide NP and cranberry seed oil to help calm itchiness from dry skin and lock in moisture, that consistent use helps strengthen the vulvar skin's moisture barrier, and that it is made without fragrance, sulphates, parabens or dyes. It comes in 100 ml.

Use vulvar products on the outside only, and avoid scented feminine products; see our feminine wash guide for why.

Building a simple routine

• Internal dryness: a vaginal moisturizer on the schedule its label gives, such as every 3 days for Replens.
• During sex: a water-based lubricant; the NIA notes a variety can be found at most grocery and drug stores.
• Outer skin: a vulvar moisturizer, if your vulva feels dry or itchy. DIVA pairs its Moisturizer with a Cleanser in a Hydration Duo, saying the cleanser helps wash away dried blood or sweat while preventing moisture loss after showering.
• Avoid fragrance. DIVA's products are made without fragrance, and the Office on Women's Health warns that scented tampons, pads, powders and sprays may increase the chance of a vaginal infection.
• Track what helps. If symptoms return quickly or worsen, bring notes to your doctor.

For other menopause questions, see our menopause support supplement guide.

When to see a doctor

The NIA says local vaginal treatments, such as estrogen creams, rings or tablets, are often used to treat vaginal dryness, and that the FDA has approved two nonhormone medications, ospemifene and prasterone, to treat moderate to severe painful sex caused by vaginal changes that occur with menopause.

See a doctor if dryness persists despite over-the-counter products, if sex is painful, or if you have bleeding, unusual discharge or itching, which can have other causes.

What to look for when you buy

Questions people ask

What is the difference between a vaginal moisturizer and lube?

The NIA says moisturizers are used regularly, not just during sex; lubricants relieve dryness during sex.

How often do I use a vaginal moisturizer?

Follow the label; Replens says each application lasts 3 days.

Do vaginal moisturizers contain estrogen?

Over-the-counter ones like Replens say they are estrogen-free; estrogen creams, rings or tablets are prescription treatments.

Can I use a vaginal moisturizer right before sex?

Replens recommends applying it at least 2 hours before intercourse.

What if over-the-counter products do not help?

See a doctor; the NIA lists local estrogen and two nonhormone medications for menopause-related painful sex.

Sources

• Sex and Menopause: Treatment for Symptoms (www.nia.nih.gov/health/menopause/sex-and-menopause-treatment-symptoms), National Institute on Aging
• Long-Lasting Vaginal Moisturizer (replens.com), Replens
• The Moisturizer (divacup.com), DIVA
• The Hydration Duo (divacup.com), DIVA
• Douching (womenshealth.gov), Office on Women's Health, HHS

Sources checked 2026-10-15.