Home / Supplements

Passionflower supplements: what they may help and when to avoid them

By the Life in Good Form editors. Updated 2026-10-15.

We research products from makers' specs and health sources; we do not run hands-on tests. Links to Amazon may earn us a commission at no cost to you. How this works.

Quick answerPassionflower (Passiflora incarnata) is a vine sold for anxiety, stress and sleep. The NCCIH says a small amount of research suggests it might reduce anxiety, including before surgery or dental work, and might improve total sleep time in insomnia, but conclusions are not definite. A 2020 systematic review of nine trials found most reported lower anxiety. Extract use appears possibly safe for up to 8 weeks. It can cause drowsiness and confusion, should not be used in pregnancy, and should be stopped before surgery unless a provider says otherwise.
Our picks at a glance
  • Standardized passionflower extract capsules. Best for: Adults who want a labeled, standardized extract. See options on Amazon
  • Organic passionflower capsules. Best for: Buyers who prefer certified organic herbs. See options on Amazon
  • Alcohol-free passionflower liquid extract. Best for: People who prefer drops and want to avoid alcohol. See options on Amazon

Compare the picks and what to watch out for

What passionflower is

Passionflower is a climbing vine with white and purple flowers, native to the southeastern United States and Central and South America. The National Center for Complementary and Integrative Health (NCCIH) says it has traditionally been used as a sedative and was brought to Europe after 16th-century Spanish explorers learned of it.

Today it is promoted for anxiety (including before surgery), sleep problems, stress, ADHD, pain and other conditions. NOW Foods' extract, for example, uses the aerial (above-ground) parts.

What the research shows

UseWhat the evidence says
Anxiety, including before proceduresSmall amount of research suggests it might help
InsomniaMight improve total sleep time; mixed on falling and staying asleep
ADHD, menopause, stress, fibromyalgiaNot enough evidence

NCCIH notes passionflower's effects on anxiety and other conditions have not been studied extensively.

A 2020 systematic review in Nutrients included nine clinical trials in adults, lasting from one day to 30 days. Most reported reduced anxiety after passionflower, with less effect in people with mild anxiety. No adverse effects such as memory loss were observed. The authors concluded it may help some symptoms in neuropsychiatric patients.

Safety: surgery, pregnancy and drowsiness

Reading a passionflower label

NOW Foods' Passion Flower capsules give 700 mg of Passiflora incarnata extract from the aerial parts per 2-capsule serving, standardized to at least 3.5% total flavonoids as vitexin and isovitexin. The label directs 1 to 2 capsules daily as needed.

Tips for use

What to look for when you buy

Standardized passionflower extract capsules

Best for: Adults who want a labeled, standardized extract

NOW Foods lists 700 mg of Passiflora incarnata extract per 2 capsules, standardized to at least 3.5% flavonoids, taken 1 to 2 capsules daily as needed.

Watch out: May cause drowsiness. Not for pregnancy, and stop before surgery unless your provider says otherwise.

See options on Amazon

Organic passionflower capsules

Best for: Buyers who prefer certified organic herbs

Organic vegan passionflower capsules are widely sold, an option if organic certification matters to you.

Watch out: Check that the label names Passiflora incarnata. Same drowsiness and pregnancy cautions.

See options on Amazon

Alcohol-free passionflower liquid extract

Best for: People who prefer drops and want to avoid alcohol

Liquid extracts let you adjust the amount, and alcohol-free versions avoid the alcohol in many tinctures.

Watch out: Strength is not standardized across brands. Do not combine with other sedatives.

See options on Amazon
When to talk to a doctor: Do not use passionflower during pregnancy, and stop it before surgery unless your provider says otherwise. It can cause drowsiness and confusion, so avoid driving and alcohol, and talk with your provider if you take sedatives or other medicines.

Questions people ask

Is passionflower a calming supplement?
It is used that way. A small amount of research suggests it might reduce anxiety, and a 2020 review found most of nine trials reported lower anxiety.
Does passionflower help sleep?
It might improve total sleep time in adults with insomnia, but results on falling and staying asleep are mixed.
Is passionflower safe?
Extract use may be safe for up to 8 weeks. Side effects include drowsiness, dizziness and confusion. Do not use it during pregnancy.
Can I take passionflower before surgery?
Avoid it unless your provider recommends it. It might interact with anesthesia; tell your provider if you took it within 2 weeks of surgery.
Is passionflower the same as passion fruit?
No. Calming supplements use Passiflora incarnata, the species NCCIH describes. Check the label rather than assuming any passion fruit product is the same.
Can passionflower help ADHD or menopause symptoms?
NCCIH says there is not enough evidence to know whether passionflower helps ADHD, menopausal symptoms, fibromyalgia, heart failure or stress.
How long can I take passionflower?
NCCIH says passionflower tea may be safe for up to 7 nights and daily extract use for up to 8 weeks. Longer use has not been well studied.

Sources

Sources checked 2026-10-15.