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Nutritional yeast: fortified vs unfortified, vitamin B12 and how to use it

By the Life in Good Form editors. Updated 2026-10-15.

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Quick answerNutritional yeast is a deactivated yeast sold as yellow flakes or powder with a savory, cheesy flavor. The biggest difference between products is fortification: the NIH Office of Dietary Supplements (ODS) says some nutritional yeasts are fortified with vitamin B12, which matters for vegans because only animal foods have B12 naturally. USDA label data show Bob's Red Mill Large Flake, a fortified product, at 116 mcg of B12 per 100 grams, while Frontier's flakes list no B12. Both list substantial protein and fiber. Check the Nutrition Facts label to see whether B12 has been added.
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Fortified vs unfortified

Per 100 grams (USDA label data)Bob's Red Mill Large FlakeFrontier Co-op flakes
Protein53.3 g45.4 g
Fiber20.0 g18.2 g
Vitamin B12116 mcgNot listed
Thiamin79.0 mgNot listed
Niacin307 mgNot listed
Sodium167 mg0.0 mg

Details are from USDA FoodData Central branded food entries, which convert label values to 100 grams. Label serving sizes are much smaller: 15 g for Bob's Red Mill and 11 g for Frontier.

Nutritional yeast and vitamin B12

The ODS says vitamin B12 helps keep the body's blood and nerve cells healthy and helps make DNA. It lists some breakfast cereals, nutritional yeasts and other foods as fortified with B12, and says to check the Nutrition Facts label to find out if a food has added B12.

People who eat little or no animal foods, such as vegetarians and vegans, might not get enough B12 from their diets, the ODS says, since only animal foods have it naturally. If you rely on nutritional yeast for B12, choose a fortified product and confirm B12 on the label. The ODS lists 2.4 mcg a day as the recommended amount for adults, 2.6 mcg in pregnancy.

How much B12 different ages need

The ODS lists average daily recommended amounts of vitamin B12 in micrograms (mcg) by age: 0.9 mcg for children 1 to 3 years, 1.2 mcg for children 4 to 8, 1.8 mcg for children 9 to 13, and 2.4 mcg for teens 14 to 18 and adults, rising to 2.6 mcg in pregnancy. Fortified nutritional yeast can contribute toward these amounts, but products differ widely, so read the label rather than assuming every brand is fortified. Families cooking for vegan children should talk with a pediatrician or dietitian about reliable B12 sources.

How to use nutritional yeast

For more plant protein, see our hemp hearts guide and plant-based protein powder guide.

Reading the label

For B vitamin supplements, see our sublingual vitamin B12 guide.

Who should be careful

The ODS notes that vitamin B12 deficiency affects between 3% and 43% of older adults, and that people over 50 should get most of their B12 from fortified foods or supplements, since many older adults do not have enough stomach acid to absorb B12 naturally present in food. Fortified nutritional yeast is one such fortified food, but ask your doctor about testing if you are at risk.

Fortified flakes contain large amounts of some B vitamins per 100 grams, so measure servings rather than eating it by the cup, and tell your doctor about all fortified foods and supplements you use.

Storing nutritional yeast

Keep flakes in a sealed container in a cool, dry, dark place, and follow the package's best-by date. Moisture makes flakes clump. A shaker jar keeps portions small at the table. For other pantry staples, see our chia seeds guide and ground flax seeds guide.

What to look for when you buy

Bob's Red Mill Large Flake Nutritional Yeast

Best for: A fortified flake with B12

USDA label data list 116 mcg B12 and 53.3 g protein per 100 grams.

Watch out: Measure servings; it is heavily fortified.

See options on Amazon

Frontier Co-op Nutritional Yeast Flakes

Best for: People who prefer unfortified flakes

USDA label data list 45.4 g protein and 18.2 g fiber per 100 grams with no B12 listed.

Watch out: Not a B12 source; use another if you are vegan.

See options on Amazon

Glass spice shaker jar

Best for: Sprinkling small portions

Label servings are small, such as 11 g or 15 g, so a shaker helps control portions.

Watch out: Keep it dry to prevent clumping.

See options on Amazon
When to talk to a doctor: If you follow a vegan diet, are over 50, pregnant or have a digestive condition, ask your doctor about vitamin B12 testing and whether fortified foods are enough.

Questions people ask

Is nutritional yeast a good source of B12?
Only if fortified; the ODS says some nutritional yeasts are fortified, so check the label.
How much protein is in nutritional yeast?
USDA label data list 45.4 to 53.3 g per 100 grams for two brands.
Is nutritional yeast good for vegans?
Fortified flakes can help, since the ODS says vegans might not get enough B12.
How much B12 do adults need?
The ODS lists 2.4 mcg a day for adults and 2.6 mcg in pregnancy.
What does nutritional yeast taste like?
Savory and cheesy, which is why it is popular on popcorn and in vegan sauces.

Sources

Sources checked 2026-10-15.