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Lidocaine pain relief patches

By the Life in Good Form editors. Updated 2026-10-15.

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Quick answerOver-the-counter lidocaine patches contain lidocaine 4%, a topical anesthetic that numbs the skin for temporary pain relief. The Salonpas label says to use 1 patch at a time, up to 3 to 4 times daily, and remove it after at most 8 hours; the Aspercreme label adds that used patches can still contain drug that may seriously harm children or pets, so fold and throw them away. Do not use with a heating pad, on damaged skin or under a tight bandage, and stop if you get rash, blistering or severe burning.
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What a lidocaine patch does

Lidocaine is a local anesthetic. OTC patches list lidocaine 4% as a topical anesthetic for the temporary relief of pain. Salonpas describes its gel-patch as numbing relief and sizes it at 3 15/16 by 5 1/2 inches.

A 2021 review in Drug Design, Development and Therapy notes that topical lidocaine has limited absorption and few whole-body side effects, is approved in several countries for nerve pain after shingles (post-herpetic neuralgia), and has some evidence in post-surgical pain, diabetic nerve pain, carpal tunnel syndrome, chronic low back pain and osteoarthritis.

The review describes topical lidocaine as an attractive option for vulnerable patients because so little reaches the bloodstream, and as something that can be used alone or alongside other medicines and non-drug approaches. The Salonpas box lists the back, neck, shoulders, knees and elbows as places to use its patch.

Two OTC patches compared

Label detailSalonpas Lidocaine 4%Aspercreme Lidocaine XL
ActiveLidocaine 4%Lidocaine 4%
How many1 patch at a time1 patch on your body at a time
How oftenNot more than 3 to 4 times dailyNot more than 3 to 4 times daily
Wear timeRemove after at most 8 hoursFollow label directions
Ages12 and over12 and older

Details are from DailyMed labels. Aspercreme also says not to use it together with other topical analgesics.

How to apply one

For menthol and salicylate rubs, see our muscle rub cream guide; do not use them on the same area at the same time.

Warnings on the label

Safe disposal around children and pets

The Aspercreme label warns that used patches may still contain drug that can cause serious harm if a child or pet swallows them. It says to fold the sticky ends together before throwing a used patch away, and to keep patches out of reach of children and pets. If a patch is swallowed, get medical help or contact a Poison Control Center right away.

Store unused patches as the label directs; Salonpas says to avoid direct sunlight and excessive moisture.

When to stop and see a doctor

For ongoing nerve pain, ask your doctor about prescription options, which the 2021 review discusses.

What to look for when you buy

Salonpas Lidocaine 4% gel-patch

Best for: Up to 8 hours of numbing on one sore area

The label lists lidocaine 4%, 1 patch at a time, removed after at most 8 hours, 3 15/16 by 5 1/2 inches.

Watch out: Not with a heating pad; stop for rash or blistering.

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Aspercreme Lidocaine XL patch

Best for: People who prefer an XL-size patch

The label lists lidocaine 4% with a step-by-step peel-and-place backing.

Watch out: Fold used patches and keep them away from children and pets.

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4% lidocaine patch multi-pack

Best for: Regular use on the same area

OTC 4% lidocaine patches are widely sold in multi-count boxes.

Watch out: Check the label's wear time and daily limit before use.

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When to talk to a doctor: Use only one patch at a time and never with heat or on broken skin. Keep new and used patches away from children and pets, and see a doctor for pain lasting more than 7 days or for skin blistering.

Questions people ask

How long can I leave a lidocaine patch on?
The Salonpas label says remove it after at most 8 hours.
Can I use two lidocaine patches at once?
No. Both labels say to use only 1 patch at a time on your body.
Can I use a heating pad with a lidocaine patch?
No. The labels say not to use one with a heating pad.
Are lidocaine patches safe for kids?
Labels say ask a doctor under 12, and used patches can harm children or pets if swallowed.
Do lidocaine patches work for back pain?
A 2021 review found some evidence in chronic low back pain; see a doctor if pain lasts more than 7 days.

Sources

Sources checked 2026-10-15.