Home / Personal care

Hand sanitizer: the 60% alcohol rule, how to use it and its limits

By the Life in Good Form editors. Updated 2026-10-15.

We research products from makers' specs and health sources; we do not run hands-on tests. Links to Amazon may earn us a commission at no cost to you. How this works.

Quick answerIf soap and water are not available, the CDC says to use a hand sanitizer with at least 60% alcohol, which you can confirm on the product label. Put enough on your palm to cover all surfaces of your hands and rub until dry, which takes around 20 seconds. Sanitizer does not get rid of all germs: the CDC says soap and water work better against norovirus, Cryptosporidium and Clostridioides difficile, and when hands are visibly dirty or greasy. Supervise young children so they do not swallow it.
Our picks at a glance

Compare the picks and what to watch out for

Check the alcohol percentage

The CDC says to use a hand sanitizer with at least 60% alcohol, and that you can tell by checking the product label. On a Drug Facts label, look at the active ingredient line. Purell Advanced Hand Sanitizer Fragrance Free, for example, lists ethyl alcohol 70% v/v as its active ingredient, with the purpose antimicrobial and the use to reduce bacteria on the skin.

Also check the inactive ingredients if you have sensitive skin. Purell's fragrance-free label lists water, isopropyl alcohol, caprylyl glycol, glycerin, isopropyl myristate and tocopheryl acetate among them, with no fragrance listed.

How to use hand sanitizer

The CDC's steps are:

The CDC says not to rinse or wipe off hand sanitizer before it is dry, because it may not work well against germs. Purell's label says the same in short: place product on hands and rub until dry.

When soap and water work better

SituationUseWhy, per the CDC
Hands visibly dirty or greasySoap and waterSanitizer may not be as effective
Norovirus, Cryptosporidium or C. difficileSoap and waterSoap and water remove these germs better
Chemicals like pesticides or leadSoap and waterSanitizer might not remove them
No sink available, hands not visibly dirtySanitizer with at least 60% alcoholUse it when soap and water are unavailable

The CDC adds that if a handwashing station is available, you should wash your hands with soap and water instead. For washing, see our antibacterial hand soap guide.

Label warnings

The CDC also says to supervise young children when they use hand sanitizer to prevent swallowing alcohol.

Gel, foam or spray

Hand sanitizers come as gels, foams and sprays, and labels differ by product, so read the active ingredient and directions on the one you buy. Whatever the format, the CDC's 60% minimum and rub-until-dry steps apply.

If a sanitizer irritates your skin, the Purell label says to stop use and ask a doctor if irritation or rash appears and lasts. For a gentle wash when you can get to a sink, see our body wash guide, and for dry, cracked hands our paraffin bath guide.

Storing and carrying sanitizer

Because sanitizer is flammable, store it away from heat and flame, as the label warns. Keep travel bottles capped and out of reach of children, and check the active ingredient and percentage on every new bottle rather than assuming a brand's formula is the same across products.

Sanitizer is a backup for clean hands, not a replacement for handwashing when you can get to a sink.

Key times to clean your hands, per the CDC, include before and after eating food, after using the toilet, after blowing your nose, coughing or sneezing, after touching garbage, and before and after treating a cut or wound. Use soap and water when you can, and sanitizer when you cannot.

What to look for when you buy

Purell Advanced Hand Sanitizer (fragrance free)

Best for: Everyday use when no sink is available

Its Drug Facts label lists ethyl alcohol 70% v/v, above the CDC's 60% minimum.

Watch out: Flammable; keep away from fire and children.

See options on Amazon

Travel-size hand sanitizer bottles

Best for: Bags, cars and travel

Small bottles make it easier to follow the CDC's advice to sanitize when soap and water are not available.

Watch out: Check the label shows at least 60% alcohol.

See options on Amazon

Hand sanitizer pump bottle

Best for: Homes and offices

A pump makes it easy to dispense enough to cover all surfaces of your hands, as the CDC advises.

Watch out: Still wash with soap and water when hands are dirty or greasy.

See options on Amazon
When to talk to a doctor: Keep hand sanitizer away from children and flames. If it is swallowed, get medical help or contact Poison Control right away.

Questions people ask

What percentage of alcohol should hand sanitizer have?
The CDC says at least 60% alcohol; check the active ingredient on the label.
How long should I rub hand sanitizer?
Until your hands are dry, which the CDC says should take around 20 seconds.
Is hand sanitizer as good as washing hands?
Not always; the CDC says soap and water work better against norovirus, Cryptosporidium and C. difficile, and on dirty or greasy hands.
Can I wipe off hand sanitizer?
The CDC says not to rinse or wipe it off before it is dry.
Is hand sanitizer safe for kids?
Supervise young children to prevent swallowing alcohol, and call Poison Control if swallowed, per the CDC and the label.

Sources

Sources checked 2026-10-15.